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Can you get into the system in 'safe' mode? Boot the PC and repeatedly hit F8 just after the BIOS to interupt the boot. From the plain text menu you can choose safe mode.
The system will boot a minimal system and no normal startup programs, and hopefully viruses/trojans, will not start. You can then do a full AV scan of the system. Unfortunately you can't usually install applications whilct in safe mode. So, you'll have to hope that you can run an AV scan to clear up the system.
Another option is if you know a friend who has a clean PC with up-to-date AV software you could whip out your hard drive and hook it up to their PC, normally done by connecting it in place of a CD drive and then runing an AV scan etc on it. Once it's cleaned up you can return it to your PC.
Good luck and let us know things go.
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